news | 2020-12-22
Dominoes that fall, a domino reaction.

Amino-Supported Palladium Catalyst for Chemo- and Stereoselective Domino Reactions

In this work an amino-supported palladium catalyst was used for the stereoselective synthesis of cyclopentenols via an oxidative domino reaction. These compounds are key substructures and synthons of many bioactive compounds.

Palladium was immobilized either on mesocellular foam or on crystalline nanocellulose and the two catalyst preparations gave very similar results. There was a remarkable recyclability of the heterogeneous palladium catalyst, where the kinetics of the reaction was almost identical in the first and seventh run.

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